KEGG   REACTION: R06537
Entry
R06537                      Reaction                               
Name
apigenin,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (3'-hydroxylating)
Definition
Apigenin + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Luteolin + [Oxidized NADPH---hemoprotein reductase] + H2O
Equation
C01477 + C03024 + C00007 <=> C01514 + C03161 + C00001
Comment
flavonoid 3'-hydroxylase
Reaction class
RC00001  C00005_C00006
RC00046  C01477_C01514
Enzyme
1.14.14.81      1.14.14.82
Pathway
rn00941  Flavonoid biosynthesis
rn00944  Flavone and flavonol biosynthesis
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.14  With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.14.81
     R06537  Apigenin + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Luteolin + [Oxidized NADPH---hemoprotein reductase] + H2O
    1.14.14.82
     R06537  Apigenin + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Luteolin + [Oxidized NADPH---hemoprotein reductase] + H2O
IUBMB reaction hierarchy [BR:br08202]
 1. Oxidoreductase reactions
  1.14.14.82
   R03615  Flavonoid <=> 3'-Hydroxyflavonoid
    R06537  Apigenin <=> Luteolin
Orthology
K05280  flavonoid 3'-monooxygenase [EC:1.14.14.82]
K13083  flavonoid 3',5'-hydroxylase [EC:1.14.14.81]

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (8)   
   KEGG PATHWAY (8)   
Chemical substance (6)   
   KEGG COMPOUND (6)   
Chemical reaction (4)   
   KEGG ENZYME (2)   
   KEGG RCLASS (2)   
Gene (530)   
   KEGG ORTHOLOGY (2)   
   KEGG GENES (528)   
All databases (550)   

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